发明名称 |
Bicyclic pyrazole and isoxazole derivatives as antitumor and antineurodegenerative agents |
摘要 |
Bicyclic pyrazole and isoxazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases mediated by HSP90 protein, like cancer and neurodegenerative disorders. |
申请公布号 |
US8309578(B2) |
申请公布日期 |
2012.11.13 |
申请号 |
US200913130614 |
申请日期 |
2009.11.19 |
申请人 |
MANTEGANI SERGIO;BRASCA MARIA GABRIELLA;CASUSCELLI FRANCESCO;FERGUSON RON;POSTERI HELENA;VISCO CARLO;CASALE ELENA;ZUCCOTTO FABIO;NERVIANO MEDICAL SCIENCES S.R.L. |
发明人 |
MANTEGANI SERGIO;BRASCA MARIA GABRIELLA;CASUSCELLI FRANCESCO;FERGUSON RON;POSTERI HELENA;VISCO CARLO;CASALE ELENA;ZUCCOTTO FABIO |
分类号 |
A61K31/4355;A61K31/437;C07D471/04;C07D487/04;C07D498/04 |
主分类号 |
A61K31/4355 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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