发明名称 Bicyclic pyrazole and isoxazole derivatives as antitumor and antineurodegenerative agents
摘要 Bicyclic pyrazole and isoxazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases mediated by HSP90 protein, like cancer and neurodegenerative disorders.
申请公布号 US8309578(B2) 申请公布日期 2012.11.13
申请号 US200913130614 申请日期 2009.11.19
申请人 MANTEGANI SERGIO;BRASCA MARIA GABRIELLA;CASUSCELLI FRANCESCO;FERGUSON RON;POSTERI HELENA;VISCO CARLO;CASALE ELENA;ZUCCOTTO FABIO;NERVIANO MEDICAL SCIENCES S.R.L. 发明人 MANTEGANI SERGIO;BRASCA MARIA GABRIELLA;CASUSCELLI FRANCESCO;FERGUSON RON;POSTERI HELENA;VISCO CARLO;CASALE ELENA;ZUCCOTTO FABIO
分类号 A61K31/4355;A61K31/437;C07D471/04;C07D487/04;C07D498/04 主分类号 A61K31/4355
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