| 发明名称 |
SELECTIVE OXIDATION OF C-H BONDS OF MODIFIED SUBSTRATES BY P450 MONOOXYGENASE |
| 摘要 |
The present invention provides regio- and stereoselective oxidation of unactivated C—H bonds using an engineered mutant cytochrome P450 monooxygenase and an engineered substrate. |
| 申请公布号 |
US2012190635(A1) |
申请公布日期 |
2012.07.26 |
| 申请号 |
US201013388308 |
申请日期 |
2010.09.27 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
LI SHENGYING;SHERMAN DAVID H.;MONTGOMERY JOHN;CHAULAGAIN MANI R.;KNAUFF ALLISON R. |
| 分类号 |
A61K31/704;A61K31/13;A61K31/133;A61K31/7028;A61K31/7034;A61K31/7048;A61P31/04;C07C217/52;C07H15/10;C07H15/20;C07H15/203;C07H15/24;C07H17/08;C07J41/00;C12N9/02;C12P19/44;C12P19/56;C12P19/62;C12P33/20 |
主分类号 |
A61K31/704 |
| 代理机构 |
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