发明名称 INHIBITOR(S) OF TRANSPORTERS OR UPTAKE OF MONOAMINERGIC NEUROTRANSMITTERS
摘要 The present disclosure concerns a compound, or a pharmaceutically acceptable salt thereof, having a formula: where at least one of R1-R4 is a heterocycle, at least one of R1-R4 is an aryl group coupled to the ring by a linker atom, functional group, or other moiety, or where none of R1-R4 is an amide, and any and all combinations thereof. Remaining R1-R4 substituents independently are aliphatic, substituted aliphatic, amine, substituted amine, aryl, substituted aryl, cyclic, substituted cyclic, halide, heteroaryl, substituted heteroaryl, heterocyclic, substituted heterocyclic, hydrogen or hydroxyl. A method for treating a subject also is provided comprising administering a disclosed compound or compounds, or a prodrug that is converted into the disclosed compound or compounds, or a composition comprising the compound, compounds, or prodrugs thereof, to a subject. A method for making disclosed compounds also is provided.
申请公布号 US2012190725(A1) 申请公布日期 2012.07.26
申请号 US201213355371 申请日期 2012.01.20
申请人 WHITE JAMES DAVID;WONG DAVID T.;CHAN DAVID B.;YANG JONGTAE;JUNIKU RAJAN;STATE UNIVERSITY;STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON 发明人 WHITE JAMES DAVID;WONG DAVID T.;CHAN DAVID B.;YANG JONGTAE;JUNIKU RAJAN
分类号 A61K31/381;A61P3/00;A61P3/04;A61P13/00;A61P25/00;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/30;A61P25/32;A61P25/34;A61P25/36;C07D333/16;C07D333/20;C07D333/24 主分类号 A61K31/381
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