| 摘要 |
In one aspect, the present invention provides a housing system for conducting high throughput animal experiments. The housing system includes a home cage, at least one rotatable turnstile enclosed by housing to form two or more isolation chambers, a means for animal identification, and one or more action stations functionally coupled to one or more isolation chambers. The turnstile includes a plurality of one or more separation members rotatable about a vertical axis, each isolation chamber bounded by one or more separation members. The action stations contain one or more devices facilitating completion of at least one animal-directed or experimentor-initiated action. In a preferred embodiment, the home cage is sufficiently sized to house a plurality of small animals, such as mice. Tunnel passageways may be connected to the home cage, including one or more tunnel passageways containing a rotatable turnstile. Additional embodiments include rotatable turnstiles, rotatable turnstile assemblies, and methods of conducting high throughput animal experiments using the devices and systems described herein. |
