Provided herein are animals expressing light-responsive opsin proteins in the basal lateral amygdala of the brain and methods for producing the same wherein illumination of the light-responsive opsin proteins causes anxiety in the animal. Also provided herein are methods for alleviating and inducing anxiety in an animal as well as methods for screening for a compound that alleviates anxiety in an animal.
申请公布号
WO2012061690(A3)
申请公布日期
2012.06.28
申请号
WO2011US59298
申请日期
2011.11.04
申请人
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;TYE, KAY;FENNO, LIEF;DEISSEROTH, KARL