发明名称 |
MICROSPHERES WITH IMPROVED BIOAVAILABILITY CONTAINING POORLY WATER-SOLUBLE DRUGS, AND METHOD FOR PREPARING SAME |
摘要 |
A poorly soluble drug containing microsphere with improved bioavailability, an oral formulation comprising the same, and a method of preparing the same are provided, wherein the poorly soluble drug containing microsphere is a solid dispersion wherein the poorly soluble drug is dispersed in the water-soluble polymer carrier in a noncrystalline form by spray drying, thus increasing bioavailability of the poorly soluble drug. |
申请公布号 |
EP2436377(A2) |
申请公布日期 |
2012.04.04 |
申请号 |
EP20100780799 |
申请日期 |
2010.05.27 |
申请人 |
SAMYANG BIOPHARMACEUTICALS CORPORATION |
发明人 |
KIM, KYUNG-HEE;LEE, HYUN-KI;HWANG, JUN-SEOK;HWANG, SU-JONG;PAI, CHAUL-MIN |
分类号 |
A61K9/16;A61K31/522;A61K47/34;A61K47/38 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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