发明名称 PEPTIDE EPOXYKETONES FOR PROTEASOME INHIBITION
摘要 One aspect of the invention relates to inhibitors of formula (I) that preferentially inhibit immunoproteasome activity over constitutive proteasome activity. In certain embodiments, the invention relates to the treatment of immune related diseases, comprising administering a compound of the invention. In certain embodiments, the invention relates to the treatment of cancer, comprising administering a compound of the invention.
申请公布号 ZA201001834(B) 申请公布日期 2011.11.30
申请号 ZA20100001834 申请日期 2010.03.15
申请人 PROTEOLIX INC 发明人 SHENK KEVIN D;PARLATI FRANCESCO;ZHOU HAN-JIE;SYLVAIN CATHERINA;SMYTH MARK S;BENNETT MARK K;LAIDIIG GUY J
分类号 A61K;A61P;C07D;C07K 主分类号 A61K
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