发明名称 |
7-(1H-PYRAZOL-4-YL)-1,6-NAPHTHYRIDINE COMPOUNDS AS SYK INHIBITORS |
摘要 |
A compound of formula (I) or a salt thereof; which is an inhibitor of spleen tyrosine kinase (Syk) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast and/or basophil cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for instance inflammatory disease and/or allergic disorders, and in cancer therapy, specifically heme malignancies, chronic spontaneous urticaria and autoimmune conditions.
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申请公布号 |
CA2796954(A1) |
申请公布日期 |
2011.11.03 |
申请号 |
CA20112796954 |
申请日期 |
2011.04.27 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
ATKINSON, FRANCIS LOUIS;BARKER, MICHAEL DAVID;DOUAULT, CLEMENT;GARTON, NEIL STUART;LIDDLE, JOHN;PATEL, VIPULKUMAR KANTIBHAI;PRESTON, ALEXANDER GEORGE STEVEN;WILSON, DAVID MATTHEW |
分类号 |
C07D471/04;A61K31/4462;A61P19/02 |
主分类号 |
C07D471/04 |
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