| 摘要 |
The present invention relates to a novel selective synthesis of 9α-hydroxy-steroid derivatives of the general formula (I)- wherein the meaning of -A-A'- is –CH-CH- or -CH=CH- group - by the bioconversion of compounds of the general formula (II)wherein the meaning of -A-A'- is –CH-CH- or -CH=CH- group - by using Nocardia farcinica bacterium strain, deposition number of which is NCAIM (P) - B 001342, as hydroxylating microorganism in the bioconversion. |
