发明名称 |
NEUROTENSIN CONJUGATE AND USES THEREOF |
摘要 |
The present invention features a compound having the formula A-X—B, where A is peptide vector capable of enhancing transport of the compound across the blood-brain barrier or into particular cell types, X is a linker, and B is a peptide therapeutic selected from the group consisting of neurotensin, a neurotensin analog, or a neurotensin receptor agonist. The compounds of the invention can be used to treat any disease in which increased neurotensin activity is useful and can be used to induce hypothermia or analgesia. |
申请公布号 |
EP2370471(A1) |
申请公布日期 |
2011.10.05 |
申请号 |
EP20090829934 |
申请日期 |
2009.12.07 |
申请人 |
ANGIOCHEM INC. |
发明人 |
CASTAIGNE, JEAN-PAUL;DEMEULE, MICHEL;CHE, CHRISTIAN;THIOT, CARINE;GAGNON, CATHERINE |
分类号 |
C07K19/00;A61K38/16;A61K47/50;C07K7/08 |
主分类号 |
C07K19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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