SCREENING METHOD FOR THERAPEUTIC DRUG FOR HEART DISEASE

摘要

Disclosed is a method for screening candidate compounds effective as therapeutic drugs for heart disease. Using fish with specific cardiac muscle expression of a protein that changes the wavelength of emitted florescence with a stimulus, success was achieved in making regenerated damaged sites visible after the hearts of these fish were regenerably damaged without lethal consequences. Furthermore, success was achieved in quantifying the extent of the regeneration. The method for screening candidate compounds effective as therapeutic agents for heart disease can be achieved using this technique.