发明名称 |
ALLEVIATING DISORDERS WITH COMBINING AGENTS THAT INCREASE EPOXYGENATED FATTY ACIDS AND AGENTS THAT INCREASE cAMP |
摘要 |
The present invention relates to compositions and methods for promoting and enhancing the analgesic, anesthetic and anticonvulsant properties of epoxygenated fatty acids, in particular, epoxy-eicosatrienoic acids (“EETs”) and inhibitors of soluble epoxide hydrolase (“sEH”) in the presence of elevated levels of cyclic adenosine monophosphate (“cAMP”) by combining or co-administering the epoxygenated fatty acid, EET and/or inhibitor of sEH with an agent that increases intracellular levels of cAMP, e.g., a phosphodiesterase inhibitor.
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申请公布号 |
US2011230504(A1) |
申请公布日期 |
2011.09.22 |
申请号 |
US200913063459 |
申请日期 |
2009.09.11 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY |
发明人 |
HAMMOCK BRUCE D.;INCEOGLU AHMET BORA;JINKS STEVEN L. |
分类号 |
A61K31/522;A61K31/277;A61K31/336;A61K31/4015;A61K31/403;A61K31/437;A61K31/44;A61K31/451;A61P23/00;A61P25/08;A61P25/24;A61P29/00 |
主分类号 |
A61K31/522 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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