| 摘要 |
<p>Medicament comprises a reducing sugar derivative (I) in which a hydroxy group is replaced by an alkoxy group with 2-40 carbon atoms. Independent claims are also included for: (1) cosmetic treatment of skin and/or mucosa that are sensitive, irritated, intolerant, have an allergic tendency, are aged, subject to a danger signal, have a skin barrier problem, exhibit cutaneous reddening or exhibit a nonpathological immunological imbalance associated with intrinsic, extrinsic or hormonal aging, comprising applying a (I)-containing composition to the skin and/or mucosa; (2) cosmetic treatment to retard natural aging of the skin and/or prevent accelerated aging of skin subjected to exterior stresses, comprising applying a (I)-containing composition to the skin. ACTIVITY : Antiinflammatory; Antiallergic; Immunosuppressive; Dermatological; Antipruritic; Antiseborrheic; Antipsoriatic; Antiarthritic; Antirheumatic. MECHANISM OF ACTION : Leukocyte activation inhibitor; Cytokine secretion inhibitor. Pentyl rhamnoside gave 89% inhibition of PMA-induced prostaglandin E 2 release by normal human keratinocyte cells at a concentration of 1 mg/ml, and 29% inhibition at 0.02 mg/ml.</p> |
