发明名称 |
Methods for one-pot N-demethylation/N-acylation of morphine and tropane alkaloids |
摘要 |
The present invention provides a method for the N-demethylation and/or N-acylation of an N-methylated heterocycle such as morphine alkaloids or tropane alkaloids. The method comprises reacting the heterocycle with an acylating agent in the presence of a metal catalyst.
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申请公布号 |
US7999104(B2) |
申请公布日期 |
2011.08.16 |
申请号 |
US20070771191 |
申请日期 |
2007.06.29 |
申请人 |
BROCK UNIVERSITY |
发明人 |
CARROLL ROBERT JAMES;LEISCH HANNES;HUDLICKY TOMAS;COX D. PHILLIP |
分类号 |
C07D489/02;C07D489/00 |
主分类号 |
C07D489/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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