METHOD AND KIT FOR DIAGNOSING MANTLE CELL LYMPHOMA

摘要

The invention relates to a method and kit as useful tools for classifying a patient diagnosed with mantle cell lymphoma as indolent or conventional. The method comprises: a) providing a sample from a patient with MCL; b) defining the level of expression of at least one selected gene from the group consisting of: RNGTT, HDGFRP3, FARP1, HMGB3, LGALS3BP, PON2, CDK2AP1, DBN1, CNR1, CNN3, SOX11, SETMAR and CSNK1E in the sample; and c) comparing the level of expression of each of the genes measured with respect to the level of expression of the same genes in a control sample, in which the absence of expression or poor expression of the genes with respect to the same genes in the control sample indicates a clinical course of an indolent MCL.