| 发明名称 |
Single domain antibodies for nasal administration |
| 摘要 |
<p>The invention relates to a composition for administering single domain antibodies nasally or by inhalation so as to avoid inactivation, e.g. by using VHH polypeptides derived from Camelidae antibodies. The invention further relates to compositions comprising single domain antibodies against TNF, EGFR, IgE or MMP-12. Finally, the invention relates to an inhalation device comprising the single domain antibody.
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| 申请公布号 |
EP2301967(A3) |
申请公布日期 |
2011.07.13 |
| 申请号 |
EP20100178270 |
申请日期 |
2003.11.07 |
| 申请人 |
ABLYNX N.V. |
发明人 |
SILENCE, KAREN;VAECK, MARK;VAN BERGEN EN HENEGOUWEN, PAUL P.M.P. |
| 分类号 |
C07K16/42;A61K39/395;A61P11/06;A61P19/02;A61P31/06;A61P31/16;A61P35/00;A61P37/06;C07K16/10;C07K16/12;C07K16/18;C07K16/24;C07K16/28;C07K16/30;C07K16/36;C07K16/40;C07K16/46;C12N15/13;G01N33/577 |
主分类号 |
C07K16/42 |
| 代理机构 |
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代理人 |
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| 主权项 |
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