METHOD OF TREATING RECURRENT NASOPHARYNX CANCER

摘要

FIELD: medicine. ^ SUBSTANCE: invention refers to medicine, namely to oncology, and can be used for treating patients with recurrent nasopharynx cancer. The method involves administration of chemopreparations and gamma-ray teletherapy; the first therapeutic day involves intravenous drop infusion of an automyelosuspension ex temporae incubated with cisplatin at 50 mg/m2 with underlying excessive hydration and forced diuresis; 5-fluorouracil dissolved in normal saline 200 ml is infused the same day at 500 mg/m2. After one day of a pause, gamma-ray teletherapy is performed in a hyperfractionation mode taking into account a residual dose 1.5 Gy of single basic dose twice a day every 5 hours to at 5 o'clock to 65 isoGy of total basic dose. After one week of a pause, the second course of automyelochemotherapy with cisplatin at 100 mg/m2 with underlying excessive hydration and forced diuresis is performed; 5-fluorouracil 500 mg/m2, bleomycine 30 mg/m2 and adriamycin 35 mg/m2 are infused the same day. ^ EFFECT: use of the invention allows higher clinical effectiveness ensured by combined anticancer effect of the chemopreparations and additional stimulation of immune cells by the factors contained in the bone marrow. ^ 2 tbl, 1 ex