USE OF FLAVONOID GLYCOSIDE COMPOUNDS IN MANUFACTURING MEDICAMENTS FOR TREATING MALARIA

摘要

Use of flavonoid glycoside compounds in manufacturing medicaments for treating malaria is provided by the present invention, especially use in manufacturing medicaments for treating malaria caused by plasmodium. The structures of said flavonoid glycoside compounds are of one of the general formulas shown below: In the formulas, R1 is coumaroyl, trans-coumaroyl or caffeoyl; R2 is coumaroyl, trans-coumaroyl, caffeoyl or H. Demonstrated by the experiments, the flavonoid glycoside compounds have significant binding effect with FP-2 protein, thus, can be used to manufacture pharmaceutical composition for treating malaria. The pharmaceutical composition contains flavonoid glycoside compounds as active ingredients and pharmaceutically acceptable carriers. The content of active ingredients in the pharmaceutical composition is 5-95% by weight. Dosage forms of the medicaments can be tablets, granules, capsules, suspension in water or oil, syrup or injections and so on.