发明名称 |
Humanized anti-amyloid beta antibodies |
摘要 |
Humanized anti-A&bgr; antibodies derived from a murine antibody directed to a N-terminal epitope of A&bgr; are described. The humanized antibodies have reduced or no human T cell epitopes and bind A&bgr; with an affinity similar to that of the murine antibody.
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申请公布号 |
US7931899(B2) |
申请公布日期 |
2011.04.26 |
申请号 |
US20080323682 |
申请日期 |
2008.11.26 |
申请人 |
MEDTRONIC, INC |
发明人 |
SHAFER LISA LYNN;CARR FRANCIS JOSEPH;GREGSON JAMES PETER;BEMBRIDGE DAWN ANN;JONES TIM |
分类号 |
A61K39/395;C12P21/08 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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