发明名称 ANTIBODIES AGAINST CCR5 AND USE THEREOF
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a new antibody against CCR5 used as a therapeutic agent for AIDS. <P>SOLUTION: There is provided an antibody binding to human CCR5 comprising a variable heavy chain or variable light chain, characterized in that the variable heavy chain comprises CDR sequences CDR1, CDR2 and CDR3, all of which are selected from specific amino-acid sequences, wherein CDRs are selected independently of each other or are chimeric, humanized variants or fragments of the antibody. <P>COPYRIGHT: (C)2011,JPO&INPIT</p>
申请公布号 JP2011079836(A) 申请公布日期 2011.04.21
申请号 JP20100238172 申请日期 2010.10.25
申请人 F HOFFMANN LA ROCHE AG 发明人 BRANDT MICHAEL;SANKURATRI SURYANARAYANA;SCHUMACHER RALF;SEEBER STEFAN
分类号 C07K16/28;A61K39/395;A61P31/18;A61P37/04;C12N5/10;C12N15/09;C12P21/08 主分类号 C07K16/28
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