发明名称 |
INHIBITORS OF EXTRACELLULAR HSP90 |
摘要 |
<p>The present invention describes the inhibitors of extracellular Hsp90. The inhibition of extracellular Hsp90 leads to a reduction of the invasiveness of the tumor cells. Furthermore, the invention relates to the use of molecules inhibiting extracellular Hsp90 function for the manufacture of a medicament for the treatment or prevention of invasion and/or metastatic potential of cancer cells.</p> |
申请公布号 |
EP1603941(B1) |
申请公布日期 |
2011.01.05 |
申请号 |
EP20040718644 |
申请日期 |
2004.03.09 |
申请人 |
TUFTS UNIVERSITY |
发明人 |
JAY, DANIEL G.;EUSTACE, BRENDA K.;SAKURAI, TAKASHI |
分类号 |
C07K14/47;A61K31/00;A61K31/37;A61K39/395;A61K49/00;C07K16/18;C07K16/30;C12N15/10;G01N33/50 |
主分类号 |
C07K14/47 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|