发明名称 |
EXTENDED RELEASE BUCCAL BIOADHESIVE TABLET |
摘要 |
PROBLEM TO BE SOLVED: To provide a bioadhesive tablet wherein the active ingredient is protected from water or the surrounding environment. SOLUTION: The active ingredient of the bioadhesive tablet is protected from metabolism or from other degradation caused by moisture, enzymes, or pH effects and exerts bioavailability only at a controlled rate. The active ingredient is protected from moisture during its production and more importantly is protected from moisture until after a patient utilizes the tablet at a slow and controlled rate. Only a part of the active ingredient being a fraction is utilized for absorption by the gradual hydration function, and the bioadhesive tablet is protected for a long time after administration. COPYRIGHT: (C)2011,JPO&INPIT |
申请公布号 |
JP2010248231(A) |
申请公布日期 |
2010.11.04 |
申请号 |
JP20100151682 |
申请日期 |
2010.07.02 |
申请人 |
COLUMBIA LAB (BERMUDA) LTD |
发明人 |
BOLOGNA WILLIAM J;LEVINE HOWARD L;CARTIER PHILIPPE;DE ZIEGLER DOMINIQUE |
分类号 |
A61K9/22;A61K9/00;A61K9/20;A61K31/568;A61K47/02;A61K47/04;A61K47/12;A61K47/26;A61K47/30;A61K47/32;A61K47/36;A61K47/38;A61K47/48;A61P5/26;A61P9/00;A61P9/10;A61P11/06;A61P15/10;A61P19/10;A61P25/28 |
主分类号 |
A61K9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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