发明名称 EXTENDED RELEASE BUCCAL BIOADHESIVE TABLET
摘要 PROBLEM TO BE SOLVED: To provide a bioadhesive tablet wherein the active ingredient is protected from water or the surrounding environment. SOLUTION: The active ingredient of the bioadhesive tablet is protected from metabolism or from other degradation caused by moisture, enzymes, or pH effects and exerts bioavailability only at a controlled rate. The active ingredient is protected from moisture during its production and more importantly is protected from moisture until after a patient utilizes the tablet at a slow and controlled rate. Only a part of the active ingredient being a fraction is utilized for absorption by the gradual hydration function, and the bioadhesive tablet is protected for a long time after administration. COPYRIGHT: (C)2011,JPO&INPIT
申请公布号 JP2010248231(A) 申请公布日期 2010.11.04
申请号 JP20100151682 申请日期 2010.07.02
申请人 COLUMBIA LAB (BERMUDA) LTD 发明人 BOLOGNA WILLIAM J;LEVINE HOWARD L;CARTIER PHILIPPE;DE ZIEGLER DOMINIQUE
分类号 A61K9/22;A61K9/00;A61K9/20;A61K31/568;A61K47/02;A61K47/04;A61K47/12;A61K47/26;A61K47/30;A61K47/32;A61K47/36;A61K47/38;A61K47/48;A61P5/26;A61P9/00;A61P9/10;A61P11/06;A61P15/10;A61P19/10;A61P25/28 主分类号 A61K9/22
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