发明名称 |
SEROTONIN 5-HT3A RECEPTORS IN TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS |
摘要 |
Methods are provided for modulating post-natal migration of neurons. Activation of the 5-HT3A receptor increases migration, while pharmacological blockade of the 5-HT3A receptor disrupts neuroblast migration into the cortex and hippocampus. These neuroblasts mature into GABAergic interneurons, and thus are relevant to conditions associated with disturbances in 5-HT levels and GABAergic inhibition. |
申请公布号 |
WO2008020334(A3) |
申请公布日期 |
2010.10.07 |
申请号 |
WO2007IB03556 |
申请日期 |
2007.06.21 |
申请人 |
MONYER, HANNAH;INTA, DRAGOS |
发明人 |
MONYER, HANNAH;INTA, DRAGOS |
分类号 |
G01N33/94;G01N33/50 |
主分类号 |
G01N33/94 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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