| 发明名称 |
PHARMACEUTICAL COMPOSITION CONTAINING A STABILISED mRNA OPTIMISED FOR TRANSLATION IN ITS CODING REGIONS |
| 摘要 |
The present invention relates to a pharmaceutical composition containing an mRNA that is stabilised by sequence modifications in the translated region and is optimised for the translation. The pharmaceutical composition according to the invention is particularly suitable as an inoculating agent as well as a therapeutic agent for tissue regeneration. In addition a process is described for determining sequence modifications that serve for the stabilisation and translation optimisation of mRNA.
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| 申请公布号 |
US2010239608(A1) |
申请公布日期 |
2010.09.23 |
| 申请号 |
US20100787755 |
申请日期 |
2010.05.26 |
| 申请人 |
CUREVAC GMBH |
发明人 |
VON DER MUELBE FLORIAN;HOERR INGMAR;PASCOLO STEVE |
| 分类号 |
A61K39/21;A61K31/7105;A61K38/00;A61K38/19;A61K39/00;A61K39/12;A61K39/145;A61K39/245;A61K39/29;A61K48/00;A61P31/12;A61P31/14;A61P31/16;A61P31/18;A61P31/20;A61P31/22;A61P35/04;A61P37/04;C07H21/02;C07K14/11;C12N15/67;G06F19/18;G06F19/22 |
主分类号 |
A61K39/21 |
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