发明名称 HETEROARYL-CONTAINING TRIPEPTIDE HCV SERINE PROTEASE INHIBITORS.
摘要 <p>The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis c virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis c virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.</p>
申请公布号 MX2010008108(A) 申请公布日期 2010.09.22
申请号 MX20100008108 申请日期 2009.01.22
申请人 ENANTA PHARMACEUTICALS, INC. 发明人 YAT SUN OR;ZHE WANG;YONGHUA GAI
分类号 A61K38/00;A61K31/4965 主分类号 A61K38/00
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