| 发明名称 |
PROPHYLACTIC AND THERAPEUTIC USE OF SIRTUIN INHIBITORS IN TNF-ALPHA MEDIATED PATHOLOGIES |
| 摘要 |
The invention relates to the use of sirtuin inhibitors for reducing TNF-alpha production by cells and organisms. The invention also concerns prophylactic and therapeutic applications of sirtuin inhibitors in TNF-alpha mediated pathologies, such as various inflammatory and autoimmune disorders.
|
| 申请公布号 |
US2010137345(A1) |
申请公布日期 |
2010.06.03 |
| 申请号 |
US20080599910 |
申请日期 |
2008.05.14 |
| 申请人 |
UNIVERSITE LIBRE DE BRUXELLES |
发明人 |
LEO OBERDAN;GALLI MARA;VAN GOOL FREDERIC |
| 分类号 |
A61K31/513;A61K31/166;A61K31/37;A61P1/00;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P25/00;A61P27/02;A61P29/00;A61P31/00;A61P37/00;A61P37/08;C07C237/30;C07D239/56;C07D311/20;C12N5/071 |
主分类号 |
A61K31/513 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
