VASCULAR EMBOLUS OF PACLITAXEL-SODIUM ALGINATE MICROSPHERE AND ITS PREPARATION

摘要

Vascular embolus of Paclitaxel-sodium alginate microsphere and its preparation A sodium alginate microsphere vascular embolus containing paclitaxel. The preparation of it consists of the following steps: preparing the solution of paclitaxel, sodium alginate and dilvalent metal cations such as BaCl2 etc. by order;mixing the palitaxle solution and sodium alginate solution,and then mixing them with the curing solution of BaCl2 or CaC12 and the like. Then the obtained is the paclitaxel-containing sodium alginate microsphere vascular embolus. The carrier materials of the vascular embolus according to the invention are natural extracts and have good biocompatibility and are biodegradable; the side effect of the pharmaceutic loaded by them is minimal, and it is therefore suitable for the vascular embolism and chemotherapy against the tumor.