SYNTHESIS OF L-(CARBAZOL-4-YLOXY)-3-[[2-(O- METHOXYPHENOXY)ETHYL]AMINO]-2-PROPANOL

摘要

The present invention relates to an improved process for the preparation of Carvedilol, wherein, the process involves the use of organic base in the reaction of 4-(oxirane-2ylmethoxy)-9H-carbazole with 2-(2-methoxyphenoxy) ethylamine in presence of a solvent. While preparing Carvedilol minimum amount of bis-impurity was obtained without purification.