A METHOD FOR SCREENING COMPOUNDS COMPRISING THE USE OF PICORNAVIRUS PROTEASE 2A
摘要
A method of screening compounds or molecules comprising the steps of: translating a sequence encoding the amino acid sequence comprising SEQ ID No. 29 in a translation system in the presence of a test compound or molecule; and analysing the translation product(s) for the presence of one or more of (a) a peptide comprising the amino acids Pro-Gly at the C terminus and a peptide comprising the amino acid Pro at the N terminus: or (b) a peptide comprising the amino acid sequence of SEQ ID No. 29.
申请公布号
WO2009128056(A3)
申请公布日期
2010.01.21
申请号
WO2009IE00019
申请日期
2009.04.17
申请人
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS;ATKINS, JOHN;RYAN, MARTIN;LOUGHRAN, GARY