| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a cyclic GMP (cGMP) detection method in a wider application range in a cGMP detection system. <P>SOLUTION: The method comprises a process for introducing a polypeptide having a domain N containing a partial sequence at the N terminal side of luciferase, a cGMP binding domain and a domain C containing a partial sequence at the C terminal side of luciferase in this order, bonded in this order and making the domain N complementary to the domain C into a cGMP detection system; a process for introducing luciferin into the cGMP detection system; and a process for detecting luminescence from the cGMP detection system. <P>COPYRIGHT: (C)2010,JPO&INPIT |
