| 摘要 |
The present invention provides an antagonist for endothelin which is considered to have a relationship to hypertension, Buerger disease, asthma, eyegrounds diseases, and the like. The endothelin antagonist contains 15-keto-prostaglandin E compounds, especially 13, 14-dihydro-15-keto-16-mono or dihalo-prostaglandins.
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