发明名称 |
METHODS FOR INCREASING CYTIDINE LEVELS IN VIVO AND TREATING CYTIDINE-DEPENDENT HUMAN DISEASES |
摘要 |
Methods of treating certain neurological diseases using exogenous uridine or a uridine source alone as a precursor of endogenous cytidine, particularly in the human brain, are disclosed. Methods are also disclosed wherein exogenous uridine or a uridine source is combined either with drugs increasing uridine availability or with compounds that serve as a source of choline in phospholipid synthesis. |
申请公布号 |
CA2339008(C) |
申请公布日期 |
2009.12.15 |
申请号 |
CA19992339008 |
申请日期 |
1999.07.30 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
WATKINS, CAROL;WURTMAN, RICHARD J. |
分类号 |
A61K31/7072;C07H19/067;A61K31/14;A61K31/221;A61K31/24;A61K31/515;A61K31/551;A61K31/661;A61K31/685;A61K31/688;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7068;A61P9/10;A61P25/00;A61P25/14;A61P25/18;A61P25/22;A61P25/24;A61P25/28 |
主分类号 |
A61K31/7072 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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