| 摘要 |
The present invention provides compositions and methods for the treatment of cancer, and is predicated at least in part on the use of gene fusion regions as therapeutic targets. The fusion region target may be physically embodied at the level of DNA, RNA or protein. Typically the fusion region is specific to cancerous or precancerous cells, meaning that any therapy directed to the target may not significantly affect non-cancerous tissue. The fusion region may be targeted by protein or nucleic acid molecules capable of specifically binding to the region.
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