发明名称 |
MOLEKULARDIAGNOSEVERFAHREN UND BEHANDLUNG VON DEMENZ MIT LEWY-KÖRPERCHEN |
摘要 |
The present invention describes methods of molecular diagnosis of a concrete form of a-synucleinopathy, the dementia with Lewy bodies (DLB), associated to the levels of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) or the alteration of its ubiquityl-ligase activity. It also refers to the use of compounds that permit the modification of the UCH-L1 levels or of the enzymatic activity of UCH-L1. This invention has application in the diagnosis and treatment of patients suffering from DLB. |
申请公布号 |
DE602005016697(D1) |
申请公布日期 |
2009.10.29 |
申请号 |
DE20056016697T |
申请日期 |
2005.07.18 |
申请人 |
ORYZON GENOMICS, S.A. |
发明人 |
MAES, TAMARA;BUESA ARJOL, CARLOS;BARRACHINA, M.;FERRER ABIZANDA, ISIDRO |
分类号 |
G01N33/68;C07K14/47 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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