发明名称 |
HETEROCYCLIC BENZENESULPHONAMIDE COMPOUNDS AS BRADYKININ ANTAGONISTS |
摘要 |
The invention concerns compounds selected among the group consisting of (i) compounds of formula (I) wherein: Het1 represents a nitrogenous heterocycle with 5 apices, in particular imidazole, pyrazole, or triazole; Het2 represen ts a nitrogenous heterocycle with 4, 5 or 6 apices, selected among the heterocycles: (II) wherein R1 and R2 are defined as mentioned in the description; and (ii) thei r additive salts. The invention also concerns the method for preparing said compounds and their use in therapy, in particular for treating pathologies involving bradykinine. (see formula I) (see formula II)
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申请公布号 |
CA2371853(C) |
申请公布日期 |
2009.09.29 |
申请号 |
CA20002371853 |
申请日期 |
2000.02.17 |
申请人 |
FOURNIER INDUSTRIE ET SANTE |
发明人 |
DODEY, PIERRE;BARTH, MARTINE;BONDOUX, MICHEL |
分类号 |
C07D401/14;A61K31/4709;A61K31/496;A61K31/5377;A61P25/04;A61P29/00;C07D413/14;C07D417/14;C07D521/00 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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