<p>The present invention relates to a method of producing an amidated peptide product by producing a precursor having a C-terminal glycine using genetically engineered host cells and thereafter converting said glycine to an amino group to produce a peptide amide. A method for direct expression of a peptide product into a culture medium is also provided.</p>
申请公布号
EP2088188(A1)
申请公布日期
2009.08.12
申请号
EP20090006784
申请日期
1998.04.15
申请人
UNIGENE LABORATORIES, INC.
发明人
MEHTA, NOZAR, M.;RAY, MARTHA, V., L.;MEENAN, CHRISTOPHER, P.;CONSALVO, ANGELO, P.