发明名称 |
Combination therapy to treat hepatitis B virus |
摘要 |
The present invention is directed to a method for treating hepatitis B virus infection in humans comprising administering a synergistically effective amount of agents having known anti-hepatitis B virus activity in combination or alternation. Specifically, the invention is directed to a method for treating hepatitis B virus infection comprising administering FTC in combination or alternation with penciclovir, famciclovir or Bis-POM-PMEA. Additionally, the invention is directed to a method for treating hepatitis B virus infection comprising administering L-FMAU in combination or alternation with DAPD, penciclovir or Bis-POM-PMEA. The invention is further directed to a method for treating hepatitis B virus infection comprising administering DAPD in combination or alternation with Bis-POM-PMEA.
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申请公布号 |
US7572800(B2) |
申请公布日期 |
2009.08.11 |
申请号 |
US20030374363 |
申请日期 |
2003.02.25 |
申请人 |
GILEAD SCIENCES, INC. |
发明人 |
FURMAN PHILLIP A.;PAINTER, III GEORGE R.;BARRY DAVID W.;ROUSSEAU FRANCK |
分类号 |
A61K31/52;C07D473/16;A61K31/513;A61K31/522;A61K31/662;A61K31/675;A61K31/70;A61K45/06;A61P1/16;A61P31/12;A61P31/14;A61P35/00;C07D411/04;C07D473/18;C07D473/32;C07D473/34 |
主分类号 |
A61K31/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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