发明名称 A TOPICAL ANTIANDROGEN FOR HAIR LOSS AND OTHER HYPERANDROGENIC CONDITIONS
摘要 Substituted phenylalanines are provided comprising an hydantoin, urea or 2-hydroxyl, 2-methylpropionyl group, dimers thereof and alkyl, polyfluoroamido and haloarylamino derivatives thereof, as well as radiolabeled derivatives thereof. The compounds bind specifically to the androgen receptor and find use in indications associated with the androgen receptor, such as cell hyperplasia dependent on androgens, hirsutism, acne and androgenetic alopecia.
申请公布号 PL201173(B1) 申请公布日期 2009.03.31
申请号 PL20000350356 申请日期 2000.05.25
申请人 BIOPHYSICA, INC. 发明人 SOVAK MILOS;SELIGSON ALLEN L.;CAMPION BRIAN;BROWN JASON W.
分类号 C07C237/22;C07D295/10;A61K31/165;A61K31/167;A61K31/277;A61K31/40;A61K31/417;A61P5/00;A61P5/28;A61P17/10;A61P17/14;A61P35/00;C07C231/02;C07C237/04;C07C255/56;C07C255/60;C07C275/30;C07C317/46;C07C323/60;C07C335/08;C07C335/16;C07C335/22;C07D207/40;C07D207/408;C07D233/02;C07D233/72;C07D233/86;C07D233/88 主分类号 C07C237/22
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