发明名称 Process for the production of an abuse-proofed solid dosage form
摘要 The present invention relates to a process for the production of an abuse-proofed solid dosage form containing at least one active ingredient with potential for abuse and a synthetic or natural polymer with a breaking strength of =500 N, characterised in that a corresponding mixture is processed by melt extrusion with the assistance of a planetary-gear extruder.
申请公布号 US2008312264(A1) 申请公布日期 2008.12.18
申请号 US20080140496 申请日期 2008.06.17
申请人 GRUNENTHAL GMBH 发明人 ARKENAU-MARIC ELISABETH;BARTHOLOMAUS JOHANNES
分类号 A61K31/485 主分类号 A61K31/485
代理机构 代理人
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