| 发明名称 |
ANTIBODIES FIGHTING MONOCYTE CHEMOATTRACTANT PROTEIN-1 (MCP-1) AND THEIR APPLICATION |
| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: full-size human monoclonal antibodies against MCP-1 antigene are obtained. Antibodies are used for MCP-1 level definition in patient sample, as well as in tumour and inflammatory disease treatment. Invention allows obtainment of monoclonal antibodies highly specific to MCP-1 antigene. ^ EFFECT: efficient antibody use for treatment of the said diseases and in diagnostic purposes. ^ 16 cl, 18 dwg, 17 tbl, 11 ex |
| 申请公布号 |
RU2339647(C2) |
申请公布日期 |
2008.11.27 |
| 申请号 |
RU20050134354 |
申请日期 |
2003.08.19 |
| 申请人 |
ASTRAZENEKA AB |
发明人 |
G'JUDAS DZHIN M.;KHAAK-FRENDSHO MEHRI;FOORD ORIT;LIANG MEJNA L.;AKHLUVALIJA KIRAN;BKHAKTA SUNIL |
| 分类号 |
C07K16/24;G01N33/53;A61K39/395;A61P9/10;A61P13/12;A61P17/06;A61P19/02;A61P25/00;A61P29/00;A61P35/00;A61P35/04;A61P37/00;A61P43/00;C07K16/00;C07K17/00;C12N15/09;C12P21/08 |
主分类号 |
C07K16/24 |
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