摘要 |
The present invention provides novel peptides of specified sequence and t heir use as a signal peptide or a membrane-anchoring peptide. It also relate s to chimeric polypeptide comprising one or more such peptides and a polypep tide of interest as well as nucleic acid molecule, vectors, infectious viral particles and host cells encoding such peptides and chimeric polypeptides. The present invention also relates to a pharmaceutical composition comprisin g such elements and a pharmaceutically acceptable vehicle. The present inven tion also provides a method for recombinantly producing a polypeptide using such peptides, especially for directing expression of a polypeptide of inter est extracellularly or anchored at the surface of the plasma membrane.
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