| 发明名称 |
Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents |
| 摘要 |
The present invention is directed to acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4 -diaminocyclohexyl)-purines of the formula where Z is selected from the group consisting of -S(O)<SUB>2</SUB>-, and -C(O)-.
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| 申请公布号 |
US7429595(B2) |
申请公布日期 |
2008.09.30 |
| 申请号 |
US20030677683 |
申请日期 |
2003.10.02 |
| 申请人 |
AVENTIS PHARMACEUTICALS INC. |
发明人 |
BORCHERDING DAVID;DUMONT JENNIFER A.;PEET NORTON P.;WRIGHT PAUL S. |
| 分类号 |
C07D473/16;A61K31/52;A61P35/00;A61P35/02;A61P37/06 |
主分类号 |
C07D473/16 |
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