Pharmaceutical compositions for glucocorticoid replacement therapy
摘要
The invention relates to glucocorticoid replacement therapy and provides pharmaceutical compositions and kits designed to deliver one or more glucocorticoids to a subject in need thereon in a manner that results in serum levels of the glucocorticoid that essentially mimic that of a healthy subject for a clinically relevant period of time. The pharmaceutical compositions and kits are prepared in such a way that a first part of one or more glucocorticoids is substantially immediately released and a second part of one or more glucocorticoids is released over an extended period of time of at least about 8 hours. The invention also relates to a method for treating diseases requiring glucocorticoid treatment such as in subjects having a glucocorticoid deficiency disorder.
申请公布号
ZA200609680(B)
申请公布日期
2008.08.27
申请号
ZA20060009680
申请日期
2006.11.21
申请人
DUOCORT AB.
发明人
SKRTIC, STANKO;LENNERNAE, HANS;JOHANNSSON, GUDMUNDUR;JOHNSSON, JOERGEN;HEDNER, THOMAS