Flea head, nerve cord, hindgut and malpighian tubule nucleic acid molecules, proteins and uses thereof

摘要

The present invention relates to isolated nucleic acid molecule selected from the group consisting of:
(a) an isolated nucleic acid molecule comprising a nucleic acid sequence that hybridizes to a polynucleotide sequence encoding a protein consisting of SEQ ID NO:1873 under conditions comprising (a) hybridizing in a solution comprising IX SSC and 0% formamide, at a temperature of about 37°C and (b) washing in a solution comprising IX SSC and 0% formamide, at a temperature of about 47.5°C; and,
(b) an isolated nucleic acid molecule fully complementary in sequence to the nucleic acid molecule of (a). The invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies and inhibitory compounds. Also included are therapeutic compositions comprising such proteins, nucleic acids, or protective compounds derived from proteins of the present invention.