| 发明名称 |
Unique Integrin Binding Site in Connective Tissue Growth Factor |
| 摘要 |
The invention relates to a connective tissue growth factor peptide that encompasses a CTGF binding site for an integrin such as alpha<SUB>v</SUB>beta<SUB>3 </SUB>or alpha<SUB>5</SUB>beta<SUB>1 </SUB>and uses therefor. The invention also relates to agonists and inhibitors of the CTGF-integrin binding and methods of treating and preventing CTGF-related disorders.
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| 申请公布号 |
US2008125352(A1) |
申请公布日期 |
2008.05.29 |
| 申请号 |
US20070940833 |
申请日期 |
2007.11.15 |
| 申请人 |
NATIONWIDE CHILDREN'S HOSPITAL |
发明人 |
BRIGSTOCK DAVID R.;GAO RUNPING |
| 分类号 |
A61K38/00;A61K38/17;C07H21/04;C07K14/475;C07K14/74;C07K14/78;C07K16/00;C07K16/22;C07K16/28;C12N15/18 |
主分类号 |
A61K38/00 |
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