| 发明名称 |
Aglycosyl anti-CD154 (CD40 ligand) antibodies and uses thereof |
| 摘要 |
The invention relates to aglycosyl anti-CD154 antibodies or antibody derivatives, characterized by a modification at the conserved N-linked site in the C<SUB>H2 </SUB>domains of the Fc portion of said antibody. The invention also relates to the treatment of immune response related diseases and inhibition of unwanted immune responses with such aglycosylated anti-CD154 antibodies or antibody derivatives thereof. |
| 申请公布号 |
US2008124278(A1) |
申请公布日期 |
2008.05.29 |
| 申请号 |
US20070894619 |
申请日期 |
2007.08.20 |
| 申请人 |
|
发明人 |
TAYLOR FREDERICK R.;BENJAMIN CHRISTOPHER D.;BURKLY LINDA C.;GARBER ELLEN A. |
| 分类号 |
A61K49/00;A61K39/395;A61P35/00;A61P37/06;C07K16/28;C12P21/08 |
主分类号 |
A61K49/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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