发明名称 Production of urokinase in a three-dimensional cell culture
摘要 Embodiments of a method for the production of human urokinase are disclosed. Also disclosed are embodiments of a cell culture well-suited for use with the disclosed method. The method involves culturing urokinase-producing cells, such as immortalized human renal cells, in a cell culture. The cell culture comprises microcarrier structures and a tissue culture medium. The urokinase production is allowed to occur while the cell culture remains relatively static, i.e., the cell culture is not substantially mixed.
申请公布号 US7361493(B1) 申请公布日期 2008.04.22
申请号 US20050139102 申请日期 2005.05.26
申请人 THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF VETERANS AFFAIRS;TULANE UNIVERSITY 发明人 HAMMOND TIMOTHY G.;ALLEN PATRICIA L.
分类号 C12N9/12 主分类号 C12N9/12
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