| 发明名称 |
Use of IL-18 inhibitors for the treatment of Chron's disease |
| 摘要 |
Disclosed is the use of an IL-18 inhibitor selected from IL-18 binding proteins, isoforms, muteins, fused proteins, functional derivatives, active fractions or circularly permutated derivatives thereof having essentially the same activity as an IL-18 binding protein for the manufacture of a medicament for the treatment and/or prevention of Crohn's disease.
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| 申请公布号 |
NZ546294(A) |
申请公布日期 |
2008.02.29 |
| 申请号 |
NZ20010546294 |
申请日期 |
2001.02.20 |
| 申请人 |
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.;YEDA RESEARCH AND DEVELOPMENT COMPANY LTD |
发明人 |
CHVATCHKO, YOLANDE;DINARELLO, CHARLES;PLATER-ZYBERK, CHRISTINE;VAN DEVENTER, SANTER;RUBINSTEIN, MENACHEM;NOVICK, DANIELA;KIM, SOO-HYUN |
| 分类号 |
C12N15/09;A61K31/00;A61K35/12;A61K38/00;A61K38/17;A61K38/21;A61K39/395;A61K45/00;A61K48/00;A61P1/04;A61P1/16;A61P19/02;A61P19/08;A61P25/32;A61P29/00;A61P31/12;A61P37/00;A61P37/02;A61P43/00;C07K16/24;C12N15/63;(IPC1-7):A61K39/395 |
主分类号 |
C12N15/09 |
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