发明名称 |
METHOD FOR THE PREPARATION OF TAXOL AND ITS DERIVATIVES |
摘要 |
The invention refers to a process for the preparation of compounds of formul a (I), wherein R1 is an aryl or heteroaryl group; R2 is hydrogen, arylcarbonyl, heteroarylcarbonyl or C1-C6 alkoxycarbonyl; R3 is hydrogen or acetyl; the process comprising reacting a compound of formula (II) with a compound of formula (III), wherein each of R8 and R9 independently is a hydroxy protecting group in the presence of a condensing agent so obtaining a compound of formula (IV).
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申请公布号 |
CA2197467(C) |
申请公布日期 |
2008.02.12 |
申请号 |
CA19962197467 |
申请日期 |
1996.06.04 |
申请人 |
PHARMACIA & UPJOHN S.P.A. |
发明人 |
GENNARI, CESARE;MONGELLI, NICOLA;VANOTTI, ERMES;VULPETTI, ANNA |
分类号 |
C07D263/16;C07D263/04;C07D263/06;C07D263/26;C07D305/14;C07D413/12 |
主分类号 |
C07D263/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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