发明名称 |
A HOST CELL COMPRISING A VECTOR FOR PRODUCTION OF PROTEINS REQUIRING GAMMA-CARBOXYLATION |
摘要 |
The present invention relates a host cell comprising an expression vector comprising a nucleic acid molecule encoding a protein requiring gamma-carboxylation and associated expression control sequences and a nucleic acid molecule encoding a vitamin K epoxido reductase and associated expression control sequences and a nucleic acid molecule encoding a gamma-glutamyl carboxylase and associated control sequences. The invention further relates to a method of producing a protein requiring gamma-carboxylation in high yields. |
申请公布号 |
KR20080002949(A) |
申请公布日期 |
2008.01.04 |
申请号 |
KR20077026252 |
申请日期 |
2006.04.10 |
申请人 |
ASTRAZENECA AB |
发明人 |
LOEVGREN ANN |
分类号 |
C12N9/64;C12N15/57;C12N15/67 |
主分类号 |
C12N9/64 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|